IDENTIFICATION OF A BRAZIL-NUT ALLERGEN IN TRANSGENIC SOYBEANS PDF

Eliot M. Allergenic reactions to proteins expressed in GM crops has been one of the prominent concerns among biotechnology critics and a concern of regulatory agencies. Soybeans like many plants have intrinsic allergens that present problems for sensitive people. Current GM crops, including soybean, have not been shown to add any additional allergenic risk beyond the intrinsic risks already present.

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Skip to search form Skip to main content You are currently offline. Some features of the site may not work correctly. The nutritional quality of soybeans Glycine max is compromised by a relative deficiency of methionine in the protein fraction of the seeds. To improve the nutritional quality, methionine-rich 2S albumin from the Brazil nut Bertholletia excelsa has been introduced into transgenic soybeans.

Since the Brazil nut is a known allergenic food, we assessed the allergenicity of the 2S albumin. Save to Library. Create Alert. Launch Research Feed. Share This Paper. Figures and Tables from this paper. Figures and Tables. Citations Publications citing this paper. References Publications referenced by this paper. Accumulation of a Brazil nut albumin in seeds of transgenic canola results in enhanced levels of seed protein methionine Susan B.

Allergenicity and tolerance to proteins from brazil nut Bertholletia excelsa H. Identification of soybean allergens by immunoblotting with sera from soy-allergic adults. Anne M. Bush Medicine, Biology International archives of allergy and applied immunology Multiplicity of allergens in peanuts.

Howden Medicine The Journal of allergy and clinical immunology A chimeric gene encoding the methionine-rich 2S albumin of the Brazil nut Bertlrolletia excelsa H. Enhancement of the methionine content of seed proteins by the expression of a chimeric gene encoding a methionine-rich protein in transgenic plants Susan B. Altenbach , K. Pearson , Gabrielle Meeker , Lisa C.

Allergenicity of various peanut products as determined by RAST inhibition. Julie A. Jones , John W. Yunginger Medicine The Journal of allergy and clinical immunology Pearson , Filomena W.

Plant food protein engineering. Shunsaku Utsumi Biology, Medicine Advances in food and nutrition research Related Papers. By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy , Terms of Service , and Dataset License.

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IDENTIFICATION OF A BRAZIL-NUT ALLERGEN IN TRANSGENIC SOYBEANS

Background: The nutritional quality of soybeans Glycine max is compromised by a relative deficiency of methionine in the protein fraction of the seeds. To improve the nutritional quality, methionine-rich 2S albumin from the Brazil nut Betholletia excelsa has been introduced into transgenic soybeans. Since the Brazil nut is a known allergenic food, we assessed the allergenicity of the 2S albumin. Methods: The ability of proteins in transgenic and non-transgenic soybeans, Brazil nuts, and purified 2S albumin to bind to IgE in serum from subjects allergic to Brazil nuts was determined by radioallergosorbent tests 4 subjects and sodium dodecyl sulfate-polyacrylamide-gel electrophoresis 9 subjects with immunoblotting and autoradiography. Three subjects also underwent skin-prick testing with extracts of soybean, transgenic soybean, and Brazil nut.

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Identification of a Brazil-nut Allergen in Transgenic Soybeans

Julie A. Nordlee 15 Estimated H-index: Estimated H-index: Find in Lib. Add to Collection. Background The nutritional quality of soybeans Glycine max is compromised by a relative deficiency of methionine in the protein fraction of the seeds. To improve the nutritional quality, methionine-rich 2S albumin from the Brazil nut Bertholletia excelsa has been introduced into transgenic soybeans.

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Identification of a Brazil-nut allergen in transgenic soybeans

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