Fue aislado de la piel de cerdo por primera vez por Meyer y Chaffee en El donante activo del grupo sulfato es el 3'-fosfoadenosina-5'-fosfosulfato PAPS. Sin embargo, se han observados niveles de entre 0. Se ha observado que en los paciente sin estos componentes ha aumentado la fragilidad de la piel. La decorina se ha identificado como un objetivo para Borrelia burgdorferi , el agente de la enfermedad de Lyme.

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Dermatán sulfato

El gen ACAN forma parte de la familia de la lectina. Su masa molecular es de kDa aproximadamente. Estos residuos responsables de las modificaciones se encuentran situados en regiones diferentes. Presenta una estructura molecular similar a una escobilla. El gen agrecano humano contiene exactamente 19 exones y 18 intrones. En el otro extremo C-terminal terminal carboxilo encontraremos un tercer dominio globular G3 separado por un amplio dominio KS y CS.


2012, Número 3

Publicado: abr 30, Guest I, Uetrecht J. Med Hypotheses. Hay ED. Biogenesis and organization of extracellular matrix. Junqueira LC, Carneiro J. Rio de Janeiro: Guanabara Koogan;

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